Canagliflozin

Canagliflozin

  • Active Ingredient – Canagliflozin
  • Generic Name – Canagliflozin
  • Drug Class – SGLT-2 Inhibitors
  • Indication- Type 2 Diabetes Treatment
  • Dosage – 100 mg orally OD should be taken before the breakfast. Dose can be increased to 300 mg once daily for more glycemic control in Type 2 diabetes.
  • Storage – StoreThis Medicine at room temperature (10-30°C)

Introduction

Canagliflozin is an orally administerable SGLT-2 Inhibitors. Canagliflozin is used in the treatment of Type – 2 Diabetic Patients. Canagliflozin retards the transporter protein SGLT-2 in kidneys. Canagliflozin decreases renal glucose reabsorption as a result urinary glucose secretes more. Canagliflozin has a lower risk of hypoglycaemia. Canagliflozin decreases  the risk of heart attack, stroke or death in people who have diabetes type 2 suffering  with heart and end-stage kidney disease.

Side effects of Canagliflozin

  • Ketoacidosis
  • Lower limb Amputations
  • More thirst and more urination
  • Nausea and vomiting
  • Skin redness and itching
  • Urinary tract infections
  • Urosepsis and polynephritis
  • Yeast infections and itching of vagina
  • Bone Fracture
  • Fatigue
  • Fournier’s  gangrene

 

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